About 4 results found for searched term "CAN508" (0.124 seconds)
Cat.No. | Name | Target |
---|---|---|
M11247 | CAN508 | CDK |
CAN508 was an effective AND ATP-competitive inhibitor of CDK9/cyclin T1 with IC50 of 0.35 μM. CAN508 is 38 times more selective for CDK9/cyclin T1 than other CDK/cyclin. CAN508 has antitumor activity. | ||
M11522 | Rhodamine 123 | Fluorescent Dye |
RH-123; R-22420 | ||
Rhodamine 123 is a membrane-permeable cationic green fluorescent dye that can be easily absorbed by active mitochondria without cytotoxicity. The maximum excitation/emission wavelength is 508nm/530nm, giving green fluorescence for observation of mitochondria, stored in refrigerators (-5 to -30°C) and protected from light. | ||
M28259 | (Rac)-CCT 250863 | Apoptosis |
(Rac)-CCT 250863 (compound rac-21) is a selective and reversible NEK 2 inhibitor with an IC50 of 0.073 µM. (Rac)-CCT 250863 shows good effects of inducing cell cycle arrest and also can antiproliferative in cells (Pomalidomide sensitive/resistant). (Rac)-CCT 250863 induces apoptosis when combines with Pomalidomide. | ||
M29907 | RNF5 inhibitor inh-02 | E1/E2/E3 Enzyme |
RNF5 inhibitor inh-02 is a potent inhibitor of E3 ubiquitin ligase RNF5/RMA1. RNF5 inhibitor inh-02 leads to significant F508del-CFTR rescue (EC50=2.2 uM) in bronchial epithelial cells homozygous for the F508del mutation. RNF5 inhibitor inh-02 can be used for cystic fibrosis research. |
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